<b>Prevalence of low-penetrant germline </b><i><b>TP53</b></i><b> D49H mutation in Japanese cancer </b><b>patients </b>
نویسندگان
چکیده
منابع مشابه
Germline mutation of BRCA1 in Japanese breast cancer families.
We analyzed germline mutations of the BRCA1 gene in 18 Japanese breast cancer families and two Japanese breast-ovarian cancer families. In two site-specific breast cancer families, the same mutation was detected; a nonsense mutation at codon 63 encoding a truncated small protein. It was demonstrated that the mutant allele cosegregated with breast cancer patients within a family and was absent i...
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ژورنال
عنوان ژورنال: Biomedical Research
سال: 2016
ISSN: 0388-6107,1880-313X
DOI: 10.2220/biomedres.37.259